In April 1947 a log cabin, formerly a diner, and some four acres were purchased to establish a Catholic Mission, St. Ann, for the community of Williamsburg, Ohio. To prepare the log cabin for the celebration of the Mass, parishioners added pews and fashioned a simple albeit beautiful altar, and on October 12, 1947, Mass was celebrated for the first time by Monsignor James Hoban. The current church was completed in spring of 1959, and is designed in the Colonial American style. In 1990, St. Ann Church began to share a pastor with Holy Trinity parish in Batavia, Ohio.

On July 1, 2012, the four parish region of Holy Trinity, St. Ann, St. Louis, and St. Philomena were gathered together under the name of Clermont Catholic Communities. The overseer of this process and the pastor of this new four-parish region was Father Jerry Hiland, who up until that time had been pastor of St. Louis and St. Philomena.  Father Martin Bachman was assigned to the parish region in 2015, and in 2022, Father Thomas McCarthy was named pastor of this parish region, now known as Beacons of Light SE-5 or Holy Family Parishes.